This dataset consists of daily averages of temperature, salinity, river nitrogen inputs, velocity vectors, nutrient, oxygen, and plankton related carbon and chlorophyll a data as well as monthly averages of carbonate chemistry, including air-sea and pelagic-benthos fluxes, and plankton related carbon, nitrogen, respiration, and primary production data. This is a gridded dataset, covering the Northwest European continental shelf from 40 to 60 degrees latitude and from -19 to 13 degrees longitude, with a horizontal resolution of 7 km and 52 sigma depth levels corresponding to the Atlantic Margin Model 7 km (AMM7) domain. The data cover the period from 1990 to 2099. These outputs are downscaled projections, obtained by running the Nucleus for European Modelling of the Ocean (NEMO) and European Regional Seas Ecosystem Model (ERSEM) coupled physics-biogeochemistry climate model, forced with lateral and atmospheric boundary conditions from the Institut Pierre-Simon Laplace Coupled Model with mid-resolution, IPSL-CM5A-MR, from the Coupled Model Intercomparison Project collection, CMIP5, running under the RCP8.5 emission scenario. This dataset was generated by the Plymouth Marine Laboratory (PML) and the National Oceanography Centre (NOC), under Natural Environment Research Council (NERC) grant Resolving Climate Impacts on shelf and CoastaL sea Ecosystems, ReCICLE (grant numbers NE/M004120/1 and NE/M003477/2). The simulations were run on the ARCHER supercomputer managed by the University of Edinburgh.